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Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients
Author(s) -
Salo Ooft,
Fleur Weeber,
Krijn K. Dijkstra,
Chelsea McLean,
Sovann Kaing,
Erik van Werkhoven,
Luuk J. Schipper,
Louisa R. Hoes,
Daniël J. Vis,
Joris van de Haar,
Warner Prevoo,
Pétur Snæbjörnsson,
Daphne van der Velden,
Michelle Klein,
Myriam Chalabi,
Henk Boot,
Monique E. van Leerdam,
Haiko J. Bloemendal,
Laurens V. Beerepoot,
Lodewyk F.A. Wessels,
Edwin Cuppen,
Hans Clevers,
Emile E. Voest
Publication year - 2019
Publication title -
science translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.aay2574
Subject(s) - organoid , colorectal cancer , medicine , chemotherapy , oncology , cancer , biology , neuroscience
Tumor organoids from individual patients with metastatic colorectal cancer can help predict response to irinotecan with or without 5-fluorouracil.

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