Open AccessEngineered probiotics for local tumor delivery of checkpoint blockade nanobodies
Author(s) -
Candice R. Gurbatri,
Ioana Lia,
Rosa L. Vincent,
Courtney Coker,
Samuel Castro,
Piper M. Treuting,
Taylor E. Hinchliffe,
Nicholas Arpaia,
Tal Danino
Publication year - 2020
Publication title -
science translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.aax0876
Subject(s) - blockade , medicine , cancer research , computational biology , biology , receptor
An engineered probiotic system locally delivers checkpoint blockade nanobodies to tumors for sustained therapeutic release.
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