GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells | Zendy

Eric L. Smith | Zendy; Kim Harrington | Zendy; Mette Stæhr | Zendy; Reed Masakayan | Zendy; Jon C. Jones | Zendy; Thomas J. Long | Zendy; Khong Y. Ng | Zendy; Majid Ghoddusi | Zendy; Terence J. Purdon | Zendy; Xiuyan Wang | Zendy; Trevor Do | Zendy; Minh Thu Pham | Zendy; Jessica M. Brown | Zendy; Carlos Fernández de Larrea | Zendy; Eric J. Olson | Zendy; Elizabeth Peguero | Zendy; Pei Wang | Zendy; Hong Liu | Zendy; Yiyang Xu | Zendy; Sarah C. Garrett-Thomson | Zendy; Steven C. Almo | Zendy; HansGuido Wendel | Zendy; Isabelle Rivière | Zendy; Liu C | Zendy; Blythe Sather | Zendy; Renier J. Brentjens | Zendy

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GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells

Author(s) -

Eric L. Smith,

Kim Harrington,

Mette Stæhr,

Reed Masakayan,

Jon C. Jones,

Thomas J. Long,

Khong Y. Ng,

Majid Ghoddusi,

Terence J. Purdon,

Xiuyan Wang,

Trevor Do,

Minh Thu Pham,

Jessica M. Brown,

Carlos Fernández de Larrea,

Eric J. Olson,

Elizabeth Peguero,

Pei Wang,

Hong Liu,

Yiyang Xu,

Sarah C. Garrett-Thomson,

Steven C. Almo,

HansGuido Wendel,

Isabelle Rivière,

Liu C,

Blythe Sather,

Renier J. Brentjens

Publication year - 2019

Publication title -

science translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.819

H-Index - 216

eISSN - 1946-6242

pISSN - 1946-6234

DOI - 10.1126/scitranslmed.aau7746

Subject(s) - multiple myeloma , immunotherapy , medicine , cancer research , immunology , immune system

GPRC5D is an attractive target for immunotherapy of myeloma, and optimized GPRC5D-targeted CAR T cells eradicate myeloma xenografts.

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