Open AccessOxytocin antagonism prevents pregnancy-associated aortic dissection in a mouse model of Marfan syndrome
Author(s) -
Jennifer Habashi,
Elena Gallo MacFarlane,
Rustam Bagirzadeh,
Caitlin J. Bowen,
Nicholas D Huso,
YiChun Chen,
Djahida Bedja,
Tyler J. Creamer,
Graham Rykiel,
Maurice Manning,
David L. Huso,
Harry C. Dietz
Publication year - 2019
Publication title -
science translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.aat4822
Subject(s) - marfan syndrome , antagonism , oxytocin , aortic dissection , medicine , pregnancy , dissection (medical) , oxytocin receptor , aortic aneurysm , cardiology , surgery , receptor , aorta , biology , genetics
Protection from pregnancy-associated aortic dissection is achieved by decreasing oxytocin-induced ERK signaling in a mouse model of Marfan syndrome.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom