Open AccessUveal melanoma–associated mutations in PLCβ4 are constitutively activating and promote melanocyte proliferation and tumorigenesis
Author(s) -
H. T. Phan,
Nam Hoon Kim,
Wenhui Wei,
Gregory G. Tall,
Alan V. Smrcka
Publication year - 2021
Publication title -
science signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.659
H-Index - 154
eISSN - 1937-9145
pISSN - 1945-0877
DOI - 10.1126/scisignal.abj4243
Subject(s) - melanoma , cancer research , melanocyte , effector , cell growth , carcinogenesis , mutation , biology , cell culture , gene isoform , cancer , microbiology and biotechnology , medicine , gene , genetics
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