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Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation
Author(s) -
James Bagnall,
Christopher Boddington,
Hazel England,
Ruth Brignall,
Polly Downton,
Zainab Hussain A Alsoufi,
James Boyd,
William Rowe,
Alex Bennett,
Catherine Walker,
Antony Adamson,
Nisha Patel,
ronan.ocualain not provided,
Lorraine Schmidt,
David G. Spiller,
Dean A. Jackson,
Werner Müller,
Mark Muldoon,
Michael White,
Pawel Paszek
Publication year - 2018
Publication title -
science signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.659
H-Index - 154
eISSN - 1937-9145
pISSN - 1945-0877
DOI - 10.1126/scisignal.aaf3998
Subject(s) - tlr4 , tumor necrosis factor alpha , cytokine , microbiology and biotechnology , proinflammatory cytokine , biology , transcription factor , macrophage , signal transduction , immunology , inflammation , in vitro , gene , genetics
Competitive TNF-α uptake regulates the propagation of heterogeneous responses of macrophages in tissues.

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