Open AccesscROSs-presentation in pDCs: An energetic (m)CAT and mouse game
Author(s) -
Sunil K Joshi,
Asha Pillai
Publication year - 2018
Publication title -
science immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.83
H-Index - 51
ISSN - 2470-9468
DOI - 10.1126/sciimmunol.aau2829
Subject(s) - cross presentation , presentation (obstetrics) , reactive oxygen species , antigen , biology , cd8 , mitochondrion , antigen presentation , microbiology and biotechnology , immunology , medicine , t cell , immune system , radiology , mhc class i
pDC cross-presentation of antigens to CD8 + T cells depends on mitochondrial generation of reactive oxygen species.