Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens
Author(s) -
John Morris,
Christina M. Caragine,
Zharko Daniloski,
Júlia Domingo,
Timothy Barry,
Lu Lu,
Kyrie Davis,
Marcello Ziosi,
Dafni A. Glinos,
Stephanie Hao,
Eleni P. Mimitou,
Peter Smibert,
Kathryn Roeder,
Eugene Katsevich,
Tuuli Lappalainen,
Neville E. Sanjana
Publication year - 2023
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.adh7699
Subject(s) - biology , genome wide association study , genetics , gene , computational biology , genome , crispr , genomics , quantitative trait locus , expression quantitative trait loci , single nucleotide polymorphism , genotype
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