Treating early postnatal circuit defect delays Huntington’s disease onset and pathology in mice
Author(s) -
Barbara Y. Braz,
Doris Wennagel,
Leslie Ratié,
Diego Alves Rodrigues de Souza,
Jean-Christophe Deloulme,
Emmanuel Barbier,
Alain Buisson,
Fabien Lanté,
Sandrine Humbert
Publication year - 2022
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.abq5011
Subject(s) - glutamatergic , neuroscience , huntingtin , huntington's disease , excitatory postsynaptic potential , synapse , biology , genetically modified mouse , neurotransmission , disease , glutamate receptor , receptor , transgene , medicine , gene , inhibitory postsynaptic potential , biochemistry
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