Decoding CAR T cell phenotype using combinatorial signaling motif libraries and machine learning
Author(s) -
Kyle G. Daniels,
Shangying Wang,
Milos Simic,
Hersh K. Bhargava,
Sara Capponi,
Yurie Tonai,
Wei Yu,
Simone Bianco,
Wendell A. Lim
Publication year - 2022
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.abq0225
Subject(s) - chimeric antigen receptor , receptor , phenotype , biology , phospholipase c , motif (music) , computational biology , signal transduction , transduction (biophysics) , microbiology and biotechnology , immune system , immunotherapy , genetics , gene , biochemistry , physics , acoustics
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