Low protease activity in B cell follicles promotes retention of intact antigens after immunization | Zendy

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Low protease activity in B cell follicles promotes retention of intact antigens after immunization

Author(s) -

Aereas Aung,

Ang Cui,

Laura Maiorino,

Ava P. Amini,

Justin R. Gregory,

Maurice Bukenya,

Yiming Zhang,

Heya Lee,

Christopher A. Cottrell,

Duncan M. Morgan,

Murillo Silva,

Heikyung Suh,

Jesse D. Kirkpatrick,

Parastoo Amlashi,

Tanaka Remba,

Leah M. Froehle,

Shuhao Xiao,

Wuhbet Abraham,

Josetta Adams,

J. Christopher Love,

Phillip Huyett,

Douglas S. Kwon,

Nir Hacohen,

William R. Schief,

Sangeeta N. Bhatia,

Darrell J. Irvine

Publication year - 2023

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.abn8934

Subject(s) - antigen , germinal center , immunogen , immunization , protease , immunology , biology , antibody , follicular dendritic cells , proteolysis , immune system , b cell , virology , antigen presenting cell , t cell , biochemistry , monoclonal antibody , enzyme

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