Structure-based discovery of nonopioid analgesics acting through the α 2A -adrenergic receptor
Author(s) -
Elissa A. Fink,
Jun Xu,
Harald Hübner,
João M. Bráz,
Philipp Seemann,
Charlotte Avet,
Veronica Craik,
Dorothée Weikert,
Maximilian F. Schmidt,
Chase M. Webb,
Nataliya A. Tolmachova,
Yurii S. Moroz,
XiPing Huang,
Chakrapani Kalyanaraman,
Stefan Gahbauer,
Geng Chen,
Zheng Liu,
Matthew P. Jacobson,
John J. Irwin,
Michel Bouvier,
Yang Du,
Brian K. Shoichet,
Allan I. Basbaum,
Peter Gmeiner
Publication year - 2022
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.abn7065
Subject(s) - adrenergic , virtual screening , chemistry , adrenergic receptor , pharmacology , receptor , computational biology , bioinformatics , medicine , drug discovery , biology , biochemistry
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