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ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome
Author(s) -
Kim S. Robinson,
Gee Ann Toh,
Pritisha Rozario,
Rae Chua,
Stefan Bauernfried,
Zijin Sun,
Muhammad Jasrie Firdaus,
Shima Bayat,
Rhea Nadkarni,
Zhi Sheng Poh,
KhekChian Tham,
Cassandra R. Harapas,
Chrissie Lim,
Werncui Chu,
Celest W. S. Tay,
Kiat Yi Tan,
Tianyun Zhao,
Carine Bonnard,
Radoslaw M. Sobota,
John E. Connolly,
John Common,
Seth L. Masters,
Kaiwen W. Chen,
Lena Ho,
Bin Wu,
Veit Hornung,
Franklin L. Zhong
Publication year - 2022
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.abl6324
Subject(s) - inflammasome , pyroptosis , nlrp1 , microbiology and biotechnology , effector , phosphorylation , chemistry , nalp3 , innate immune system , immune system , biology , immunology , apoptosis , inflammation , caspase , biochemistry , programmed cell death

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