Synthetic regulatory reconstitution reveals principles of mammalian Hox cluster regulation
Author(s) -
Sudarshan Pinglay,
Milica Bulajić,
Dylan P. Rahe,
Emily Huang,
Ran Brosh,
Nicholas Mamrak,
Benjamin R. King,
Sergei German,
John Cadley,
Lila Rieber,
Nicole Easo,
Timothée Lionnet,
Shaun Mahony,
Matthew T. Maurano,
Liam J. Holt,
Esteban O. Mazzoni,
Jef D. Boeke
Publication year - 2022
Publication title -
science
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.abk2820
Subject(s) - hox gene , enhancer , biology , chromatin , ectopic expression , transcription factor , regulation of gene expression , regulatory sequence , cis regulatory module , computational biology , gene , genetics , gene cluster , genome , transcriptional regulation , microbiology and biotechnology
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