Oncometabolite d -2HG alters T cell metabolism to impair CD8 + T cell function | Zendy

Giulia Notarangelo | Zendy; Jessica B. Spinelli | Zendy; Elizabeth M. Perez | Zendy; Gregory J. Baker | Zendy; Kiran Kurmi | Zendy; Ilaria Elia | Zendy; Sylwia A. Stopka | Zendy; Gerard Baquer | Zendy; JiaRen Lin | Zendy; Alexandra J. Golby | Zendy; Shakchhi Joshi | Zendy; Heide F. Baron | Zendy; Jefte M. Drijvers | Zendy; Peter Georgiev | Zendy; Alison E. Ringel | Zendy; Elma Zaganjor | Zendy; Samuel K. McBrayer | Zendy; Peter K. Sorger | Zendy; Arlene H. Sharpe | Zendy; Kai W. Wucherpfennig | Zendy; Sandro Santagata | Zendy; Nathalie Y.R. Agar | Zendy; Mario L. Suvà | Zendy; Marcia C. Haigis | Zendy

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Oncometabolite d -2HG alters T cell metabolism to impair CD8 ⁺ T cell function

Author(s) -

Giulia Notarangelo,

Jessica B. Spinelli,

Elizabeth M. Perez,

Gregory J. Baker,

Kiran Kurmi,

Ilaria Elia,

Sylwia A. Stopka,

Gerard Baquer,

JiaRen Lin,

Alexandra J. Golby,

Shakchhi Joshi,

Heide F. Baron,

Jefte M. Drijvers,

Peter Georgiev,

Alison E. Ringel,

Elma Zaganjor,

Samuel K. McBrayer,

Peter K. Sorger,

Arlene H. Sharpe,

Kai W. Wucherpfennig,

Sandro Santagata,

Nathalie Y.R. Agar,

Mario L. Suvà,

Marcia C. Haigis

Publication year - 2022

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.abj5104

Subject(s) - isocitrate dehydrogenase , cancer research , carcinogenesis , t cell , cd8 , lactate dehydrogenase , cell , cytotoxic t cell , chemistry , biology , microbiology and biotechnology , immune system , biochemistry , enzyme , immunology , in vitro , gene

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