Comment on “Aberrant type 1 immunity drives susceptibility to mucosal fungal infections” | Zendy

Anne Puel | Zendy; JeanLaurent Casanova | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Comment on “Aberrant type 1 immunity drives susceptibility to mucosal fungal infections”

Author(s) -

Anne Puel,

JeanLaurent Casanova

Publication year - 2021

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.abi5459

Subject(s) - chronic mucocutaneous candidiasis , immunology , autoantibody , mucocutaneous zone , immunity , hygiene hypothesis , medicine , interferon , biology , disease , immune system , antibody , pathology

Breaket al . (Research Articles, 15 January 2021, eaay5731) suggest that chronic mucocutaneous candidiasis in humans with inborn errors ofAIRE and autoimmune polyendocrine syndrome type 1 is due to excessive interferon-γ production and not to autoantibodies neutralizing interleukin-17 cytokines. We argue that both claims are not conclusively supported by their data and are at odds with 35 years of study.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research