Early Chronic Low-Level Methylmercury Poisoning in Monkeys Impairs Spatial Vision | Zendy

Deborah C. Rice | Zendy; Steven G. Gilbert | Zendy

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Early Chronic Low-Level Methylmercury Poisoning in Monkeys Impairs Spatial Vision

Author(s) -

Deborah C. Rice,

Steven G. Gilbert

Publication year - 1982

Publication title -

science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 12.556

H-Index - 1186

eISSN - 1095-9203

pISSN - 0036-8075

DOI - 10.1126/science.7079739

Subject(s) - methylmercury , weaning , body weight , physiology , medicine , toxicology , toxicity , zoology , biology , ecology , bioaccumulation

Five monkeys were treated from birth with oral doses of mercury as methylmercury (50 micrograms per kilogram of body weight per day); concentrations in the blood peaked at 1.2 to 1.4 parts per million; and declined after weaning from infant formula to a steady level of 0.6 to 0.9 part per million. There were no overt signs of toxicity. When tested between 3 and 4 years of age under conditions of both high and low luminance, treated monkeys exhibited spatial vision that was impaired compared with that of control monkeys.

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