Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling
Author(s) -
Mitchell A. Moseng,
ChihChia Su,
Kerri Rios,
Meng Cui,
Meinan Lyu,
Przemysław Glaza,
Philip A. Klenotic,
Eric Delpire,
Edward Yu
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abq0952
Subject(s) - cotransporter , biophysics , cytosol , bumetanide , cytoplasm , transmembrane protein , chemistry , transporter , dimer , conformational change , polarity (international relations) , biochemistry , sodium , cell , biology , receptor , organic chemistry , gene , enzyme
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