Open AccessOrganoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery
Author(s) -
Ken Hiratsuka,
Tomoya Miyoshi,
Katharina T. Kroll,
Navin Gupta,
M. Todd Valerius,
Thomas C. Ferrante,
M Yamashita,
Jennifer A. Lewis,
Ryuji Morizane
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abq0866
Subject(s) - organoid , drug discovery , biology , drug development , transcriptome , disease , computational biology , neuroscience , pathology , medicine , bioinformatics , drug , pharmacology , gene , genetics , gene expression
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