Open AccessMitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway
Author(s) -
Wei Peng,
Alex J. Bott,
Ahmad A. Cluntun,
Jeffrey T. Morgan,
Corey N. Cunningham,
John C. Schell,
Yeyun Ouyang,
Scott B. Ficarro,
Jarrod A. Marto,
Nika N. Danial,
Ralph J. DeBerardinis,
Jared Rutter
Publication year - 2022
Publication title -
science advances
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abq0117
Subject(s) - glutaminolysis , pyruvate dehydrogenase complex , citric acid cycle , glutamine , pyruvate dehydrogenase kinase , microbiology and biotechnology , transaminase , biochemistry , biology , chemistry , metabolism , amino acid , enzyme