Open AccessA highly selective JAK3 inhibitor is developed for treating rheumatoid arthritis by suppressing γc cytokine–related JAK-STAT signal
Author(s) -
Chengjuan Chen,
Yuan Yin,
Gaona Shi,
Yu Zhou,
Shuai Shao,
Yazi Wei,
Lei Wu,
Dayong Zhang,
Lan Sun,
Tiantai Zhang
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abo4363
Subject(s) - janus kinase , janus kinase 3 , stat , cytokine , rheumatoid arthritis , jak stat signaling pathway , immunology , medicine , immune system , cytokine receptor , pharmacology , stat3 , cancer research , signal transduction , receptor , biology , t cell , tyrosine kinase , il 2 receptor , microbiology and biotechnology
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