Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress | Zendy

Shristi Shrestha | Zendy; Galina Erikson | Zendy; James Lyon | Zendy; Aliya F Spigelman | Zendy; Austin Bautista | Zendy; Jocelyn E. Manning Fox | Zendy; Cristiane dos Santos | Zendy; Maxim N. Shokhirev | Zendy; JeanPhilippe Cartailler | Zendy; Martin W. Hetzer | Zendy; Patrick E. MacDonald | Zendy; Rafael Arrojo e Drigo | Zendy

Open Access

Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress

Author(s) -

Shristi Shrestha,

Galina Erikson,

James Lyon,

Aliya F Spigelman,

Austin Bautista,

Jocelyn E. Manning Fox,

Cristiane dos Santos,

Maxim N. Shokhirev,

JeanPhilippe Cartailler,

Martin W. Hetzer,

Patrick E. MacDonald,

Rafael Arrojo e Drigo

Publication year - 2022

Publication title -

science advances

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.928

H-Index - 146

ISSN - 2375-2548

DOI - 10.1126/sciadv.abo3932

Subject(s) - beta cell , transcription factor , biology , endoplasmic reticulum , microbiology and biotechnology , islet , unfolded protein response , activating transcription factor , glucose homeostasis , endocrinology , medicine , transcription (linguistics) , insulin , gene , insulin resistance , genetics , linguistics , philosophy

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