Open AccessTargeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
Author(s) -
Neeraj Singh,
Brati Das,
John Zhou,
Xiangyou Hu,
Riqiang Yan
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abo3610
Subject(s) - microglia , pi3k/akt/mtor pathway , amyloid (mycology) , long term potentiation , reprogramming , amyloid precursor protein , chemistry , microbiology and biotechnology , neuroscience , alzheimer's disease , signal transduction , biochemistry , biology , receptor , medicine , gene , immunology , inflammation , disease , inorganic chemistry
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