Open AccessProtein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration
Author(s) -
Verena Kluever,
Belisa Russo,
Sunit Mandad,
Nisha Hemandhar-Kumar,
Mihai Alevra,
Alessandro Ori,
Silvio O. Rizzoli,
Henning Urlaub,
Anja Schneider,
Eugenio F. Fornasiero
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abn4437
Subject(s) - proteostasis , neurodegeneration , stable isotope labeling by amino acids in cell culture , neuroprotection , biology , neuroscience , brain aging , protein turnover , proteomics , protein aggregation , microbiology and biotechnology , medicine , protein biosynthesis , genetics , disease , gene , cognition
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