Open AccessTemozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas
Author(s) -
Deanna Tiek,
Beril Erdogdu,
Roham Razaghi,
Lü Jin,
Norah Sadowski,
Carla AlamilloFerrer,
J. Robert Hogg,
Bassem R. Haddad,
David H. Drewry,
Carrow I. Wells,
Julie E. Pickett,
Xiao Song,
Anshika Goenka,
Bo Hu,
Samuel Goldlust,
William J. Zuercher,
Mihaela Pertea,
Winston Timp,
ShiYuan Cheng,
Rebecca B. Riggins
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abn3471
Subject(s) - temozolomide , guanine , cancer research , dna , rna , dna repair , mutation , biology , chemistry , medicine , genetics , glioblastoma , gene , nucleotide
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