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How can same-gene mutations promote both cancer and developmental disorders?
Author(s) -
Ruth Nussinov,
ChungJung Tsai,
Hyunbum Jang
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abm2059
Subject(s) - pten , phenotype , cancer , biology , gene , mutation , genetics , mutant , cancer research , pi3k/akt/mtor pathway , bioinformatics , signal transduction
This review offers why same-gene mutations can lead to cancer and neurodevelopmental disorders and why a high risk of cancer.

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