Open AccessRB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer
Author(s) -
Chenkui Miao,
Takuya Tsujino,
Tomoaki Takai,
Fu Gui,
Takeshi Tsutsumi,
Zsófia Sztupinszki,
Zengjun Wang,
Haruhito Azuma,
Zoltán Szállási,
Kent W. Mouw,
Lee Zou,
Adam S. Kibel,
Jia Li
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abl9794
Subject(s) - parp inhibitor , poly adp ribose polymerase , loss function , cancer research , biology , prostate cancer , cancer cell , genome instability , dna repair , cancer , polymerase , microbiology and biotechnology , genetics , gene , dna damage , dna , phenotype
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