Open AccessTwo diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor
Author(s) -
Markus Welcker,
Baiyun Wang,
Domniţa-Valeria Rusnac,
Yasser Hussaini,
Jherek Swanger,
Ning Zheng,
Bruce E. Clurman
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abl7872
Subject(s) - degron , ubiquitin ligase , ubiquitin , biology , serine , phosphorylation , carcinogenesis , suppressor , cancer research , microbiology and biotechnology , genetics , gene