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Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy
Author(s) -
Thomas S.C. Ng,
Huiyu Hu,
Stefan Kronister,
Chanseo Lee,
Ran Li,
Luca Gerosa,
Sylwia A. Stopka,
Danielle M. Burgenske,
Ishaan Khurana,
Michael S. Regan,
Sreeram Vallabhaneni,
Niharika Putta,
Ella Scott,
Dylan Matvey,
Anita GiobbieHurder,
Rainer H. Köhler,
Jann N. Sarkaria,
Sareh Parangi,
Peter K. Sorger,
Nathalie Y.R. Agar,
Heather A. Jacene,
Ryan J. Sullivan,
Elizabeth I. Buchbinder,
Hannes Mikula,
Ralph Weissleder,
Miles A. Miller
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abl6339
Subject(s) - combination therapy , differential (mechanical device) , computational biology , penetration (warfare) , cancer research , medicine , computer science , biology , pharmacology , mathematics , physics , operations research , thermodynamics

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