Efficient healing of large osseous segmental defects using optimized chemically modified messenger RNA encoding BMP-2
Author(s) -
Rodolfo E. De la Vega,
Martijn van Griensven,
Wen Zhang,
Michael J. Coenen,
Christopher V. Nagelli,
Joseph A. Panos,
Carlos Julio Peniche Silva,
Johannes Geiger,
Christian Plank,
Christopher H. Evans,
Elizabeth R. Balmayor
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abl6242
Subject(s) - endochondral ossification , bone morphogenetic protein , bone morphogenetic protein 2 , intramembranous ossification , bone healing , messenger rna , bone morphogenetic protein 7 , bone remodeling , ossification , microbiology and biotechnology , human bone , heterotopic ossification , chemistry , medicine , anatomy , biology , cartilage , biochemistry , gene , in vitro
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