Open AccessGenetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
Author(s) -
E. Sandra Chocrón,
Erin Munkácsy,
Harper S. Kim,
Przemysław Karpowicz,
Nisi Jiang,
Candice E. Van Skike,
Nicholas DeRosa,
Andy Banh,
Juan Pablo Palavicini,
Paweł Wityk,
Leszek Kalinowski,
Verónica Galván,
Paweł A. Osmulski,
Elżbieta Jankowska,
Maria Gaczyńska,
Andrew M. Pickering
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abk2252
Subject(s) - proteostasis , proteasome , genetically modified mouse , microbiology and biotechnology , neurodegeneration , transgene , biology , neuroscience , programmed cell death , medicine , disease , pathology , apoptosis , biochemistry , gene
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