Neuronal C/EBPβ/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression
Author(s) -
Yiyuan Xia,
Hiroshi Qadota,
Zhi-Hao Wang,
Pai Liu,
Xia Liu,
Karen X. Ye,
Courtney J. Matheny,
Ken Berglund,
Shan Ping Yu,
Derek Drake,
David A. Bennett,
Xiaochuan Wang,
Bruce A. Yankner,
Guy M. Benian,
Keqiang Ye
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abj8658
Subject(s) - biology , neuroscience , genetically modified mouse , longevity , cognitive decline , degeneration (medical) , neuroprotection , endocrinology , microbiology and biotechnology , medicine , transgene , disease , gene , genetics , dementia , pathology
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