Open AccessFrizzled BRET sensors based on bioorthogonal labeling of unnatural amino acids reveal WNT-induced dynamics of the cysteine-rich domain
Author(s) -
Maria Kowalski-Jahn,
Hannes Schihada,
Ainoleena Turku,
Thomas Huber,
Thomas P. Sakmar,
Gunnar Schulte
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abj7917
Subject(s) - frizzled , cysteine , amino acid , bioorthogonal chemistry , domain (mathematical analysis) , wnt signaling pathway , chemistry , computational biology , biochemistry , microbiology and biotechnology , biology , combinatorial chemistry , signal transduction , mathematical analysis , mathematics , click chemistry , enzyme
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