Open AccessLoss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells
Author(s) -
Yan Sun,
Xiaolin Lin,
Bangdong Liu,
Yaxuan Zhang,
Wěi Li,
Sheng Zhang,
Falian He,
Han Tian,
Xun Zhu,
Ximeng Liu,
Jueheng Wu,
Junchao Cai,
Mengfeng Li
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abj6877
Subject(s) - haematopoiesis , stem cell , hematopoietic stem cell , biology , phenotype , atf4 , microbiology and biotechnology , immunology , cancer research , unfolded protein response , genetics , endoplasmic reticulum , gene