Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca 2+ efflux and disrupted by PSEN1 loss of function
Author(s) -
Pearl P.Y. Lie,
Lang Yoo,
Chris N. Goulbourne,
Martin J. Berg,
Philip Stavrides,
Chunfeng Huo,
JuHyun Lee,
Ralph A. Nixon
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abj5716
Subject(s) - microbiology and biotechnology , transient receptor potential channel , axoplasmic transport , endosome , lysosome , psen1 , biology , presenilin , melanosome , organelle , chemistry , neuroscience , biochemistry , medicine , alzheimer's disease , receptor , intracellular , disease , enzyme , melanin
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