Open AccessTransplanted organoids empower human preclinical assessment of drug candidate for the clinic
Author(s) -
Amy Westerling-Bui,
Eva M. Fast,
Thomas W. Soare,
Srinivasan P Venkatachalan,
Michael DeRan,
Alyssa Fanelli,
Sergii Kyrychenko,
Hien G. Hoang,
Grinal M. Corriea,
Wei Zhang,
Maolin Yu,
Matthew H. Daniels,
G. Malojcic,
Xin-Ru Pan-Zhou,
Mark W. Ledeboer,
Jean-Christophe Harmange,
Maheswarareddy Emani,
Thomas T. Tibbitts,
John F. Reilly,
Peter Mündel
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abj5633
Subject(s) - organoid , drug , pharmacology , medicine , drug discovery , transplantation , pharmacokinetics , pharmacodynamics , humanized mouse , drug development , clinical trial , biology , bioinformatics , immunology , immune system , neuroscience
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