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Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models
Author(s) -
Shivendra V. Singh,
Waise Quarni,
Maria Goralski,
Shibiao Wan,
Hongjian Jin,
Lee-Ann Van de Velde,
Jie Fang,
Qiong Wu,
Ahmed AbuZaid,
Tingting Wang,
Ravi K. Singh,
David Craft,
Yiping Fan,
Thomas Confer,
Melissa Johnson,
Walter J. Akers,
Ruoning Wang,
Peter J. Murray,
Paul G. Thomas,
Deepak Nijhawan,
Andrew M. Davidoff,
Jun Yang
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abj5405
Subject(s) - neuroblastoma , spliceosome , degradation (telecommunications) , computational biology , biology , cancer research , bioinformatics , computer science , genetics , rna splicing , gene , rna , cell culture , telecommunications
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