Open AccessA lethal mouse model for evaluating vaccine-associated enhanced respiratory disease during SARS-CoV-2 infection
Author(s) -
Naoko IwataYoshikawa,
Nozomi Shiwa,
Tsuyoshi Sekizuka,
Kaori Sano,
Akira Ainai,
Takuya Hemmi,
Michiyo Kataoka,
Makoto Kuroda,
Hideki Hasegawa,
Tadaki Suzuki,
Noriyo Nagata
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abh3827
Subject(s) - immunology , immune system , medicine , immunopathology , virology , respiratory disease , antibody , adjuvant , pathogenesis , immunization , coronavirus , disease , biology , infectious disease (medical specialty) , lung , covid-19 , pathology
Eosinophilic immunopathology was induced by TH 2-shifted immune response and inadequate neutralizing antibody in BALB/c mice.
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