Open AccessAnti-EGFR VHH-armed death receptor ligand–engineered allogeneic stem cells have therapeutic efficacy in diverse brain metastatic breast cancers
Author(s) -
Yohei Kitamura,
Nobuhiko Kanaya,
Susana Moleirinho,
Wanlu Du,
Clemens Reinshagen,
Nada Attia,
Agnieszka Bronisz,
Esther Revai Lechtich,
Hikaru Sasaki,
Joana L. Mora,
Priscilla K. Brastianos,
Jeffrey L. Falcone,
Aldebaran M. Hofer,
Arnaldo Franco,
Khalid Shah
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abe8671
Subject(s) - micrometastasis , medicine , cancer research , metastatic breast cancer , stem cell , breast cancer , cancer stem cell , cancer , biology , genetics
This study presents a mechanism-based receptor-targeted cellular therapy approach to treat breast to brain metastasis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom