Late-stage stitching enabled by manganese-catalyzed C─H activation: Peptide ligation and access to cyclopeptides
Author(s) -
Nikolaos Kaplaneris,
Felix Kaltenhäuser,
Giedre Sirvinskaite,
Shuang Fan,
Tiago De Oliveira,
LenaChristin Conradi,
Lutz Ackermann
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abe6202
Subject(s) - manganese , image stitching , catalysis , combinatorial chemistry , peptide , chemistry , ligation , biochemistry , biology , organic chemistry , computer science , microbiology and biotechnology , artificial intelligence
Earth-abundant manganese catalyst enabled the expedient synthesis of cyclic peptides via activation of inert C─H bonds.
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