Open AccessNaked mole rat TRF1 safeguards glycolytic capacity and telomere replication under low oxygen
Author(s) -
Adeline Augereau,
Marco Mariotti,
Mélanie Pousse,
Doria Filipponi,
Frédérick Libert,
Benjamin Beck,
Vera Gorbunova,
Éric Gilson,
Vadim N. Gladyshev
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abe0174
Subject(s) - mole , oxygen , glycolysis , hypoxia (environmental) , biology , telomere , microbiology and biotechnology , biophysics , chemistry , metabolism , genetics , dna , biochemistry , organic chemistry
Naked mole rat TRF1 enhances telomeric and metabolic functions in hypoxia through an evolutionary gain of function.
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