Tumor immunological phenotype signature-based high-throughput screening for the discovery of combination immunotherapy compounds
Author(s) -
Haiyan Wang,
Shasha Li,
Qianyu Wang,
Zhengshuo Jin,
Wei Shao,
Yan Gao,
Lu Li,
Kequan Lin,
Lin Zhu,
Huili Wang,
Xuebin Liao,
Dong Wang
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abd7851
Subject(s) - immunotherapy , high throughput screening , drug discovery , immune system , signature (topology) , throughput , computational biology , booster (rocketry) , phenotypic screening , phenotype , medicine , biology , computer science , immunology , bioinformatics , gene , genetics , telecommunications , physics , geometry , mathematics , astronomy , wireless
A high-throughput screening approach enables the discovery of tumor immune microenvironment modulator and immunotherapy booster.
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