Open AccessRIPK3-mediated inflammation is a conserved β cell response to ER stress
Author(s) -
Bingyuan Yang,
Lisette A. Maddison,
Karolina E. Zaborska,
Chunhua Dai,
Linlin Yin,
Zihan Tang,
Liqing Zang,
David A. Jacobson,
Alvin C. Powers,
Wenbiao Chen
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abd7272
Subject(s) - zebrafish , inflammation , islet , fight or flight response , unfolded protein response , microbiology and biotechnology , biology , inflammatory response , conserved sequence , stress (linguistics) , genetics , immunology , endocrinology , gene , insulin , peptide sequence , endoplasmic reticulum , linguistics , philosophy
Studies in zebrafish identify a conserved axis that mediates metabolic stress–induced pancreatic islet inflammation.
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