An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system
Author(s) -
Yoon-Jin Kim,
Qingyao Kong,
Soh Yamamoto,
Kenta Kuramoto,
Mei Huang,
Nan Wang,
Jung Hwa Hong,
Tong Xiao,
Beth Levine,
Xianxiu Qiu,
Yanxiang Zhao,
Richard J. Miller,
Hongxin Dong,
Herbert Y. Meltzer,
Ming Xu,
Congcong He
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abc8310
Subject(s) - dopamine , dopaminergic , autoreceptor , autophagy , neuroscience , dopamine receptor d2 , brain stimulation reward , reward system , regulator , microbiology and biotechnology , biology , pharmacology , chemistry , nucleus accumbens , receptor , agonist , biochemistry , apoptosis , gene
The addictive effects of cocaine are regulated by an autophagy protein and can be prevented by autophagy inhibitors.
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