Human endogenous retroviral protein triggers deficit in glutamate synapse maturation and behaviors associated with psychosis
Author(s) -
Emily M. Johansson,
Delphine Bouchet,
Ryad Tamouza,
Pierre Ellul,
AS. Morr,
Elena Avig,
Raphaële Germi,
Marion Leboyer,
Hervé Perron,
Laurent Groc
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abc0708
Subject(s) - glutamate receptor , synapse , endogeny , excitatory synapse , neuroscience , psychosis , excitatory postsynaptic potential , biology , excitatory amino acid transporter , microbiology and biotechnology , medicine , psychiatry , genetics , inhibitory postsynaptic potential , endocrinology , receptor
Retroviral protein, expressed in patients with psychotic disorders, corrupts the development of excitatory synapses and behavior.
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