Open AccessCodelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects
Author(s) -
Shaohui Deng,
Mingqiang Li,
Shuang Liu,
Jifeng Chen,
Sing Yian Chew,
Kam W. Leong,
Du Cheng
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abb4005
Subject(s) - crispr , genome editing , drug target , drug , cas9 , gene , computational biology , chlorin , biology , chemistry , cancer research , photodynamic therapy , genetics , pharmacology , organic chemistry
Codelivery of CRISPR-Cas9 and chlorin e6 achieved spatially controlled tumor-specific gene editing with synergistic drug effects.
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