Self-targeting, zwitterionic micellar dispersants enhance antibiotic killing of infectious biofilms—An intravital imaging study in mice
Author(s) -
Shuang Tian,
Linzhu Su,
Yong Liu,
Jingjing Cao,
Guang Yang,
Yijin Ren,
Fan Huang,
Jianfeng Liu,
Yingli An,
Henny C. van der Mei,
Henk J. Busscher,
Linqi Shi
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abb1112
Subject(s) - biofilm , dispersant , antibiotics , microbiology and biotechnology , micelle , chemistry , bacteria , biology , organic chemistry , aqueous solution , genetics , physics , optics , dispersion (optics)
Zwitterionic micelles find their own path through the body to disperse an infectious biofilm and enhance antibiotic efficacy.
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