Open AccessPrimary cilium remodeling mediates a cell signaling switch in differentiating neurons
Author(s) -
Gabriela Toro-Tapia,
Raman M Das
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abb0601
Subject(s) - cilium , microbiology and biotechnology , context (archaeology) , intraflagellar transport , neuroepithelial cell , biology , axon , neuroscience , mutant , neural stem cell , stem cell , genetics , paleontology , gene
Newborn neurons assemble a new primary cilium, leading to a change in the mode of Shh signaling that now directs axon extension.
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