Open AccessDaxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo
Author(s) -
Amanda R. Wasylishen,
Chang Sun,
Sydney M. Moyer,
Yuan Qi,
Gilda P. Chau,
Neeraj K. Aryal,
Florencia McAllister,
Michael P. Kim,
Michelle Barton,
Jeannelyn S. Estrella,
Xiaoping Su,
Guillermina Lozano
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aba8415
Subject(s) - death associated protein 6 , endogeny , gene silencing , endogenous retrovirus , in vivo , biology , microbiology and biotechnology , neuroscience , genetics , transcription factor , nuclear protein , gene , genome , endocrinology
Daxx loss causes coordinate dysregulation of ERVs and protein-coding genes after physiologic stress and impairs tissue recovery.
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