Open AccessGliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency
Author(s) -
Mateusz Stoszko,
Abdullah M. S. AlHatmi,
Anton Škríba,
Michael D. Röling,
Enrico Ne,
Raquel Crespo,
Yvonne M. Mueller,
Mohammad Javad Najafzadeh,
Joyce B. Kang,
Renata Ptáčková,
Elizabeth H LeMasters,
Pritha Biswas,
Alessia Bertoldi,
Tsung Wai Kan,
Elisa De Crignis,
Miroslav Šulc,
Joyce H.G. Lebbink,
Casper Rokx,
Annelies Verbon,
Wilfred F. J. van IJcken,
Peter D. Katsikis,
RobertJan Palstra,
Vladimı́r Havlı́ček,
Sybren de Hoog,
Tokameh Mahmoudi
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aba6617
Subject(s) - snrnp , p tefb , gliotoxin , biology , chemistry , biochemistry , rna , microbiology and biotechnology , ribonucleoprotein , aspergillus fumigatus , gene expression , gene , promoter
Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency.
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